During the past twenty years, an estimated 2 billion daily doses of ginkgo have been sold.  Ginkgo is extremely safe and is well tolerated by most individuals.  Side

effects and contra-indications for an average daily dose (120-240 mg) are exiguous.  The largest potential problem with Ginkgo biloba is caused by its inhibition of the platelet-activating factor; making it difficult to use in conjunction with anticoagulant drugs (Coumadin, Aspirin, etc.)  It is also potentially harmful to take Ginkgo before surgery due to blood thinning and possible bleeding complications.

 

Ginkgo contains a chemical known as ginkgotoxin found mainly in the seeds.  Uncooked, it may be linked to causing seizures.

 

Some Antidepressant medications and side effects may also be altered, good or bad, while taken in conjunction with Ginkgo.

 

Although no studies have been performed to support any restrictions on the use of Ginkgo during pregnancy or lactation, it is often discouraged. 

 

In rare cases (and usually in large doses) it is possible that Ginkgo can cause mild, transient reactions such as headache, irritability, restlessness, diarrhea, nausea, vomiting, dizziness, or skin irritations.